Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm.
نویسندگان
چکیده
We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z-Phe-Ala. It was lower on Z-Phe-Phe, Z-Glu-Tyr, Z-Glu-Phe, Z-Gly-Phe, and the lowest activity was on Z-Gly-Ala. We conclude that cathepsin A's activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity.
منابع مشابه
Hemorphin 7 reflects hemoglobin proteolysis in abdominal aortic aneurysm.
OBJECTIVE In human abdominal aortic aneurysm, the accumulation of blood-derived cells and proteases within the mural thrombus plays a pivotal role in the evolution toward vessel wall rupture. We sought to identify peptides released from abdominal aortic aneurysm specimens, characterized by an intraluminal thrombus. METHODS AND RESULTS Intraluminal thrombus samples were analyzed by differentia...
متن کاملDrug Therapy for Small Abdominal Aortic Aneurysm
Dear Editor,Abdominal aortic aneurysm is often asymptomatic, less recognized, and causes considerable mortality and morbidity, if missed. The incidence varies from country to country and the occurrence is influenced by modifiable (smoking, coronary heart disease, hypertension, dyslipidemia, and prolonged steroid therapy) and non-modifiable risk factors (increasing age, male gender, and positive...
متن کاملAn Aortoenteric Fistula Arising after Endovascular Management of a Mycotic Abdominal Aortic Aneurysm Complicated with a Psoas Abscess
Mycotic aortic aneurysms account for 1–3% of all aortic aneurysms. The management of this disease is controversial. Since open surgical repair is associated with high morbidity and mortality rates, endovascular aneurysm repair is an alternative treatment method with promising early and midterm outcomes, although its long-term durability is unknown.Secondary aortoenteric fistulas may occur iatro...
متن کاملبررسی شیوع آنوریسم آئورت شکمی در افراد بالای 65 سال مراجعهکننده به مراکز سونوگرافی بیمارستانهای آموزشی شهر بیرجند در سال 1393
Background and Aim: Abdominal aortic aneurysm is an important mortality factor especially in old men. The present study aimed at investigating prevalence of abdominal aortic aneurysm in people over 65 years old who referred to the ultrasonic centers in Birjand educational hospitals in 2014. Materials and Methods: In this cross-sectional study, 1451 individuals were willingly selected from ov...
متن کاملManagement of anesthesia in a patient with ruptured abdominal aortic aneurysm: A case report
Introduction: Abdominal aortic aneurysm is a multifactorial condition which associated with aging and atherosclerosis. During aneurysm surgery, hypotension after aortic clamp removing occure commonly that require specific treatments. This case report showes administration of blood and hemodynamic control methods after aortic unclumping during aortic aneurysm surgery. Patient: A 75–years-o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Folia histochemica et cytobiologica
دوره 49 1 شماره
صفحات -
تاریخ انتشار 2011